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  • Title: [Treatment of idiopathic thrombocytopenic purpura in adults with high-dosage immunoglobulins].
    Author: Busch FW, Ostendorf P, Schnaidt M, Wernet P, Waller HD.
    Journal: Dtsch Med Wochenschr; 1983 Aug 26; 108(34):1284-7. PubMed ID: 6684019.
    Abstract:
    Four of five patients with idiopathic thrombocytopenic purpura (ITP) responded to high-dose immunoglobulin treatment with transitory rise in platelet count to normal values, while the fifth had only minimal improvement. In the individual case there was good correlation between serum-IgG concentration and platelet count, but an influence on platelet-associated IgG could not be demonstrated with certainty. Treatment with high-dose IgG is apparently particularly suitable for patients with ITP refractory to steroids or splenectomy, in whom bleeding complications or operative procedures make a transitory rise in platelet count desirable.
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