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  • Title: Clonidine (Haemiton) as a reliable stimulus of growth hormone secretion in patients with short stature.
    Author: Keller E, Sorger D, Willgerodt H.
    Journal: Exp Clin Endocrinol; 1983 May; 81(3):315-20. PubMed ID: 6684063.
    Abstract:
    In 14 patients with short stature aged 4-14 years the effect of clonidine has been investigated. A single oral dose of 0.15 mg/m2 surface area is followed by a marked increase of hGH concentration in blood with a peak value between 60 and 90 min after the administration of the drug. The hGH increase caused by clonidine was comparable to the rise during insulin-induced hypoglycemia. In 5 patients both stimuli failed to increase hGH release. The test procedure is simple. It shows only minimum side effects and can therefore be especially recommended in outpatients.
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