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  • Title: CDP-choline: acute toxicity study.
    Author: Grau T, Romero A, Sacristán A, Ortiz JA.
    Journal: Arzneimittelforschung; 1983; 33(7A):1033-4. PubMed ID: 6684459.
    Abstract:
    The acute toxicity of a single dose of cytidine diphosphate choline (CDP-choline, citicoline, Somazina) by different administration routes in mice and rats has been studied. LD50 values were determined according to the cumulative method by Reed-Muench for mortality rate, and Pizzi's method for calculation of standard error.
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