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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: CDP-choline: repeated oral dose tolerance studies in adult healthy volunteers.
    Author: Dinsdale JR, Griffiths GK, Castelló J, Maddock J, Ortiz JA, Aylward M.
    Journal: Arzneimittelforschung; 1983; 33(7A):1061-5. PubMed ID: 6684468.
    Abstract:
    Cytidine diphosphate choline (CDP-choline, citicoline, Somazina) was administered to 12 adult healthy volunteer subjects in two short-term chronic oral dose regimens (600 mg X day-1 and 1g X day-1), each of 5 consecutive days, and compared with a corresponding regimen of matched placebo. Transient headaches were the only untoward events recorded, occurring in 4 and 5 subjects, respectively, on the lower and higher dose regimens but in only one subject during placebo administration.
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