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  • Title: [Idiopathic hypertrophic subaortic stenosis: functional condition of the left ventricle, central and pulmonary hemodynamics (an angiocardiographic study)].
    Author: Petrovskiĭ PF, Matveeva LS.
    Journal: Kardiologiia; 1983 Jul; 23(7):16-9. PubMed ID: 6684708.
    Abstract:
    Two-projectional left ventriculography, with pressure recording in the aorta, left ventricle, right chambers of the heart and the pulmonary artery, was performed in 26 patients with idiopathic hypertrophic subaortal stenosis free of intraventricular pressure gradient. Considerable left-ventricular hypertrophy associated with this condition was shown to be of "low-stress" origin and strictly concentric in nature, left ventricular systolic function keeping within normal range, and diastolic function being disordered as manifested in significantly increased filling pressure and disordered left ventricular relaxation. Disordered geometry and local contractility of the left ventricle reflected in hypercontraction of the outlet orifice, papillar muscles and posterior wall, combined with its reduced longitudinal contractility results in excessive tension of tendinous chordas and abnormal movement of the anterior mitral cusp towards the hypertrophic ventricular septum and marked mitral regurgitation.
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