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  • Title: Selection for resistance to phallolysin, a cytolytic toxin from the death-cap mushroom (Amanita phalloides).
    Author: Shier WT, DuBourdieu DJ, Kawaguchi H.
    Journal: Toxicon; 1983; 21(3):445-8. PubMed ID: 6684808.
    Abstract:
    Phallolysin-resistant variants are readily selected from unmutagenized populations of mouse fibroblasts. They exhibit partial cross-resistance to wheat germ agglutinin, a lectin with a saccharide specificity similar to phallolysin. These results are consistent with phallolysin acting by binding to cell surface glycoprotein receptors rather than by interacting directly with lipid components of the membrane.
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