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  • Title: [Combined modality for recurrent and disseminated ovarian cancer--CAPF combination chemotherapy and second-look operation].
    Author: Inagaki J, Ogawa M, Horikoshi N, Ezaki K, Inoue K, Aiba K, Komyo M, Miyamoto H, Ikeda K, Kubo H.
    Journal: Gan No Rinsho; 1983 Aug; 29(10):1291-5. PubMed ID: 6685195.
    Abstract:
    Twenty-seven patients with advanced ovarian cancer were treated with CAPF therapy consisting of CPA, ADM, CPDD, and 5-FU. Twenty patients were evaluable for responses. Fourteen patients (70%) had a complete (6 patients) or partial response (8 patients). The median survival time for responders was 12.0+ months and 4.0 for non-responders. Leukopenia and renal toxicity were dose limiting factors. A second-look operation was performed in 12 patients who had favorable results from CAPF. A combined modality with CAPF and second-look operation seemed to be promising.
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