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  • Title: The cholinergic system in rat striatum during morphine tolerance and dependence.
    Author: Schurr A, Rigor BM, Strong R, Gottesfeld Z.
    Journal: Life Sci; 1983 Dec 19; 33(25):2521-5. PubMed ID: 6685808.
    Abstract:
    Male Sprague-Dawley rats were used in the present study to assess the effects of chronic treatment of morphine on the striatal cholinergic system. The results demonstrate that neither short nor long-term morphine treatment had an effect on choline acetyltransferase (ChAT) activity or 3H-quinuclidinylbenzilate (3HQNB) binding in discrete striatal regions of the rat brain.
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