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  • Title: Physiologic and behavioral evaluation of CO euthanasia of adult dogs.
    Author: Chalifoux A, Dallaire A.
    Journal: Am J Vet Res; 1983 Dec; 44(12):2412-7. PubMed ID: 6686419.
    Abstract:
    Pure CO was used to euthanatize 18 dogs. During the procedure, physiologic parameters: EEG, ECG, arterial blood pressure, heart rate, respiratory rate, and cortisol values were monitored. Behavioral manifestations were also noted. The EEG modifications indicated a cortical voltage increase followed by rapid cerebral death. Higher heart and respiratory rates during EEG modifications indicated stress, and arterial blood pressure decreased significantly (P = less than 0.05) at the same time. Serum cortisol values were already high before the euthanasia process. Based on these observations, a precise time could not be set for unconsciousness. A gray zone, during which vocalization and agitation occurred for approximately 20 to 25 s, was 3 to 8 s in 10 dogs. These behavioral manifestations could still occur in the conscious phase.
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