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  • Title: [Condylomatous lesions of the uterine cervix: their course in 2466 patients].
    Author: de Brux J, Orth G, Croissant O, Cochard B, Ionesco M.
    Journal: Bull Cancer; 1983; 70(5):410-22. PubMed ID: 6686786.
    Abstract:
    2466 women with cervical condylomatous lesions out of the general consulting (0.7%) have been followed by the authors. The cytological and histological criteria of these lesions and the detection of the viral antigen by immunoperoxidase (positive in only about 50% of the cases), are recalled. The flat condylomas are often associated with dysplasia (CIN I, II, III). The condylomas appear in women before the age of 20. These cases increased in number between the ages of 25 to 30 and stayed high until 35. The number of condylomas associated with CIN II have their maximum between 36 and 38 years of age and decrease afterwards to age 48. The graphic is the same for CIN III. The evolution of these condylomatous lesions studied during 42 months, shows that in 1269 women with condyloma and nuclear atypia, regression occurred in 53 per cent, persistence in 37 per cent and aggravation in 10 per cent of the cases. In 762 women with CIN II, regression appeared in 39 per cent, persistence in 44 per cent and aggravation in 17 per cent of cases. In a group of 764 closely followed women, regression and aggravation in CIN I and II appeared between the 3rd and the 6th months of follow-up. Condyloma associated with CIN III were not observed after the 3rd month. Recurrence appeared however in 55 cases after insufficient ablation. Lastly, the histogenesis of these lesions and the relationship between the viral action and the host are discussed.
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