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  • Title: [Effect of thymalin and heterotransfusion on blood coagulation and fibrinolysis in thymectomized rats].
    Author: Kuznik BI, Tsybikov NN, Pisarevskaia LI, Morozov VG, Khavinson VKh.
    Journal: Biull Eksp Biol Med; 1983 Feb; 95(2):26-8. PubMed ID: 6687439.
    Abstract:
    Experiments on rats have shown that thymectomy brings about the development of hypercoagulation and inhibition of fibrinolysis. Heterotransfusion is accompanied by hypocoagulation and stimulation of fibrinolysis in both intact and thymectomized rats. At the same time fibrinolysis in thymectomized rats is stimulated to a lesser degree than in intact animals. Preinjection into thymectomized rats of the thymus low-molecular factor thymaline over one week does not only make blood coagulation and fibrinolysis return to normal but also leads to adequate changes in the hemostatic system in response to heterotransfusion.
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