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  • Title: Concurrent primary parathyroid hyperplasia and parathyroid carcinoma.
    Author: Haghighi P, Astarita RW, Wepsic HT, Wolf PL.
    Journal: Arch Pathol Lab Med; 1983 Jul; 107(7):349-50. PubMed ID: 6687992.
    Abstract:
    We noted the association of parathyroid carcinoma and primary parathyroid hyperplasia in a 53-year-old woman who had a clinical and laboratory profile of primary hyperparathyroidism. At surgery, three hyperplastic parathyroid glands were excised, one of which also demonstrated parathyroid carcinoma. Postoperatively, she was treated for persistent hypercalcemia and died of congestive cardiac failure. At autopsy, there was evidence of metastatic parathyroid carcinoma, and a further hyperplastic parathyroid gland was identified. The association of parathyroid hyperplasia and carcinoma is rare.
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