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  • Title: [The activity of microsomal hepatic cytochromes as affected by x-ray contrast media].
    Author: Bolshev VN.
    Journal: Farmakol Toksikol; 1978; 41(4):450-4. PubMed ID: 668871.
    Abstract:
    Tests on rats evidenced that X-ray contrast media can bring down the cytochrome P-450 content in the endoplasmatic reticulum of hepatic cells. The observed effect is most characteristic of cholecystrographic substances and is not linked with intesified processes of lipids peroxidation in themicrosomal membranes.
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