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  • Title: Decreased sensitivity of neurons in the basolateral amygdala to dopamine and noradrenaline iontophoresis after a kindling stimulus.
    Author: Spehlmann R, Norcross K.
    Journal: Exp Neurol; 1984 Jan; 83(1):204-10. PubMed ID: 6690320.
    Abstract:
    The depressant effects of iontophoretically applied dopamine and noradrenaline on glutamate-induced neuronal firing in the amygdaloid complex of cats were significantly reduced 1 and 2 h after induction of a local epileptiform afterdischarge of the kind used in kindling. Neuronal excitation by glutamate and depression by GABA were not significantly changed. This suggests that kindling is associated with a reduction of the inhibitory effects of endogenous catecholamines.
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