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  • Title: Pattern visual evoked potentials and spatial vision in retrobulbar neuritis and multiple sclerosis.
    Author: Neima D, Regan D.
    Journal: Arch Neurol; 1984 Feb; 41(2):198-201. PubMed ID: 6691824.
    Abstract:
    In an attempt to resolve some of the reported disagreements between visual evoked potential (VEP) recordings and Snellen visual acuity in patients with multiple sclerosis, we compared these test results with sine-wave grating-contrast sensitivity curves. Disease that depressed visual sensitivity for high spatial frequencies, sparing low spatial frequencies, was associated with depressed visual acuity and attenuated small-check VEPs in the affected eye, while large-check VEPs were not attenuated. When visual sensitivity to all spatial frequencies was depressed, both large-check and small-check VEPs were attenuated, and Snellen acuity was reduced. In general, abnormalities in the contrast sensitivity curve predicted abnormalities in VEP amplitude, but VEP delay was less accurately predicted.
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