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  • Title: Chromosome fragility in patients with sporadic unilateral retinoblastoma.
    Author: de Nuñez M, Penchaszadeh VB, Pimentel E.
    Journal: Cancer Genet Cytogenet; 1984 Feb; 11(2):139-41. PubMed ID: 6692335.
    Abstract:
    Banded karyotypes were prepared from short-term cultures of lymphocytes from the peripheral blood of ten patients with untreated sporadic unilateral retinoblastoma and ten matched controls. Different types of structural chromosome aberrations were observed in the patients, including a statistically significant increase of chromatid and isochromatid gaps and breaks.
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