These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Defining a bacteriophage T4 late promoter: absence of a "-35" region.
    Author: Elliott T, Geiduschek EP.
    Journal: Cell; 1984 Jan; 36(1):211-9. PubMed ID: 6692468.
    Abstract:
    We performed a deletion analysis to identify the minimal DNA sequence required for the function of the T4 late promoter, P23. A minipromoter derivative of P23 was constructed, containing 35 bp of T4 DNA from -18 to +17 with respect to the transcriptional initiation site. This derivative retains the TATAAATA homology and is competent to serve as a T4 late promoter both in vitro and in vivo. Its transcriptional activity in vivo is regulated identically to a wild-type plasmid-borne P23, requiring the function of T4 genes essential for late transcription, but not requiring T4 DNA replication. Recombination with the T4 phage chromosome is not significant for mini-P23 activity in vivo.
    [Abstract] [Full Text] [Related] [New Search]