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  • Title: Occurrence of a cohort phenomenon in peptic ulcer mortality from Switzerland.
    Author: Sonnenberg A.
    Journal: Gastroenterology; 1984 Mar; 86(3):398-401. PubMed ID: 6693008.
    Abstract:
    The present study was undertaken to examine whether the cohort phenomenon of peptic ulcer mortality is unique to the British population or whether it is a common feature of peptic ulcer disease. The occurrence of a cohort phenomenon was also found in data on peptic ulcer mortality from Switzerland. Swiss birth-cohorts born around 1870 and 1900 had been exposed to a maximum risk of dying of gastric and duodenal ulcer, and they carried this risk throughout their lives. By the time lag between both ulcer types, a common early determinant precipitating both diseases is made unlikely. The British cohort phenomenon was thought to result from high-risk birth-cohorts suffering mostly from the early phase of urbanization, World War I, and world economic crisis. This explanation, however, does not pertain to the high-risk cohorts from Switzerland. The nature of the determinants of peptic ulcer that occur early in the life of a cohort remains unknown.
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