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  • Title: Aging of the erythrocyte. XIX. Decrease in surface charge density of bovine erythrocytes.
    Author: Bartosz G, Grzelinska E, Bartkowiak A.
    Journal: Mech Ageing Dev; 1984 Jan; 24(1):1-7. PubMed ID: 6694439.
    Abstract:
    Decrease in electrophoretic mobility of erythrocytes, increase in Km of erythrocyte membrane acetylcholinesterase and decrease in the binding constant of 8-anilino-1-naphthalene sulfonate to erythrocyte membranes demonstrate a decrease in surface charge density of bovine erythrocytes during in vivo aging. This phenomenon seems to be species-specific; it may be due to a diminution of the sialic acid content but may also be contributed by conformational changes of membrane proteins.
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