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  • Title: Prenatal diagnosis of skeletal dysplasia by real-time ultrasound.
    Author: Wladimiroff JW, Niermeijer MF, Laar J, Jahoda M, Stewart PA.
    Journal: Obstet Gynecol; 1984 Mar; 63(3):360-4. PubMed ID: 6700859.
    Abstract:
    A control group of 165 normal pregnant women between 16 and 22 weeks' gestation was studied by real-time ultrasound scan to establish the normal length of the femur, tibia-fibula complex, humerus, and radius-ulna complex. A group of 32 pregnant women at risk for various types of fetal skeletal dysplasia were studied during the same gestational period. In three cases a structural defect was diagnosed, resulting in elective abortion. Conditions for optimal prenatal diagnosis of skeletal dysplasias are discussed.
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