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  • Title: Intravitreal 5-fluorouracil in the prevention of post-traumatic vitreous proliferation.
    Author: Avni I, Belkin M, Hercberg A, Blumenthal M.
    Journal: Ophthalmologica; 1984; 188(1):5-8. PubMed ID: 6700951.
    Abstract:
    We created double perforating injuries in both eyes of 24 rabbits. Into the vitreous cavity of one eye of each rabbit we injected 1 mg 5-fluorouracil (5-FU). After 2 months the eyes treated with 5-FU showed significantly less intraocular proliferation than the saline-treated control eyes.
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