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  • Title: [Imidazole H-2 agonists. Synthesis and activity of 2-(2-amino-4-imidazolyl)ethylamine (2-aminohistamine) dihydrochloride].
    Author: Vitali T, Impicciatore M, Plazzi PV, Bordi F, Vitto M.
    Journal: Farmaco Sci; 1984 Jan; 39(1):70-80. PubMed ID: 6705915.
    Abstract:
    The syntheses of 2-(2-amino-4-imidazolyl)ethylamine (2-aminohistamine) dihydrochloride and of the corresponding 5-methyl derivative are described. The histamine-like properties of the two salts are tested in vitro on isolated ileum and gastric fundus of guinea-pig. The results are discussed and compared with those of other H2-agonists.
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