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  • Title: [Coumarin embryopathy].
    Author: Struwe FE, Reinwein H, Stier R.
    Journal: Radiologe; 1984 Feb; 24(2):68-71. PubMed ID: 6709881.
    Abstract:
    Anticoagulant therapy using coumarin derivatives (vitamin K antagonists) during early pregnancy may result in a characteristic embryopathy appearing as a phaenocopy of chondrodysplasia punctata (Conradi-Hünermann's disease). This has been suggested in advance by observations made in newborns of mothers who had been treated previously with warfarin or acenocoumon. Similar observations made in a newborn after the mother's treatment with phencoumon in early pregnancy are described in this paper. Coumarin embryopathy is proposed as a common term.
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