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  • Title: [Spinal cord compression in malignant plasmacytic diseases. Apropos of 6 cases].
    Author: Vigneron AM, Bourgeois P, Vinceneux P, Kaplan G, Kahn MF.
    Journal: Rev Rhum Mal Osteoartic; 1984 Feb; 51(2):81-4. PubMed ID: 6710066.
    Abstract:
    Myeloma may be complicated or revealed by spinal cord compression. Out of 105 cases of myeloma admitted to this Department, 6 cases of spinal cord compression were observed, with a favourable outcome after treatment by laminectomy combined with radiotherapy. In 5 cases out of 6, spinal cord compression was either the presenting sign or occurred within the first months after diagnosis. Compression occurred in the thoracic cord in 5 cases, and in the lumbar cord in 1 case. The interval between the first symptom and diagnosis varied greatly (from a few hours to 1 year), as did the degree of paraplegia, which ranged from paraparesis to flaccid paraplegia. A favourable outcome occurs in most other reported cases, in contrast with spinal cord compression from metastases. Treatment (laminectomy-radiotherapy or both) remains controversial.
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