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  • Title: Visual evoked responses in multiple sclerosis: comparison of two methods for pattern reversal.
    Author: Nilsson BY.
    Journal: J Neurol Neurosurg Psychiatry; 1978 Jun; 41(6):499-504. PubMed ID: 671061.
    Abstract:
    Visual evoked responses have been elicited by reversal of a black and white checkerboard pattern and also by a display of light-emitting diodes (LED) generating a reversal of a pattern of illuminated red circular areas. In a control group the LED display produced responses of lower amplitude and shorter latency compared to responses to checkerboard stimulation. In patients with a definite or probable diagnosis of multiple sclerosis the stimulators were equally effective in evoking pathological responses; in patients with a possible but less certain diagnosis abnormal responses were found in a higher percentage when the LED stimulus was used. Differences in stimulus field size and in stimulus colour are discussed as possible reasons for this result.
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