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  • Title: Histologic demonstration of intradermal spirochetes in a patient with Lyme disease.
    Author: Kantoff PW, Shupack JL, Greene JB.
    Journal: Am J Med Sci; 1984; 287(2):40-2. PubMed ID: 6711586.
    Abstract:
    Spirochetal organisms were demonstrated histologically in skin biopsy specimens from a patient with Lyme disease and erythema chronicum migrans. The patient responded rapidly to penicillin G benzathine administration. Convalescent serum contained a high titer of antibody to an lxodes dammini spirochete antigen. The finding of spirochetes in an erythema chronicum migrans lesion in a patient with clinical Lyme disease supports further recent evidence that this illness is an infectious disease caused by a tick-borne bacterium. The skin biopsy may be a useful diagnostic tool in this disease.
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