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  • Title: Nicotinic stimulant, DMPP(1,1-dimethyl-4-phenylpiperazinium iodide) on the isolated bronchial smooth muscle preparation of guinea-pig.
    Author: Kizawa Y, Takayanagi I.
    Journal: Gen Pharmacol; 1984; 15(2):149-50. PubMed ID: 6714642.
    Abstract:
    Contractile responses of the isolated bronchial preparation of guinea-pig to DMPP, a nicotinic stimulant, were inhibited by ganglion blockers but not influenced by atropine, suggesting that DMPP did not bring about a contribution by stimulation of cholinergic ganglion cells. The fact that tetrodotoxin did not influence the response to DMPP suggests that a possible site of action of DMPP is not on the nerve cells.
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