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  • Title: Synthesis and antiallergic activity of some mono- and disubstituted xanthone-2-carboxylic acids.
    Author: Pfister JR, Ferraresi RW, Harrison IT, Rooks WH, Fried JH.
    Journal: J Med Chem; 1978 Jul; 21(7):669-72. PubMed ID: 671465.
    Abstract:
    A series of xanthone-2-carboxylic acids, substituted mainly with electron-withdrawing groups, has been synthesized and assayed for antiallergic activity, using the passive cutaneous anaphylaxis (PCA) reaction in the rat. The effect of substituent type and substitution pattern on PCA neutralizing capacity is presented.
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