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  • Title: [Squamous change of adenocarcinoma of the large intestine].
    Author: Yamagiwa H, Yoshimura H, Tomiyama H, Matsuzaki O, Onishi T.
    Journal: Gan No Rinsho; 1984 Mar; 30(3):233-8. PubMed ID: 6716655.
    Abstract:
    Of 986 patients with resected adenocarcinoma of the large intestine, 48 (4.8%) showed various grades of squamous change. The average age was 61.1 years, male to female ratio was 1 to 0.92. Patients experiencing this change had rectal cancer (27.1%), cancer of the sigmoid colon (22.9%), cecum (20.8%), ascending colon (16.7%) and transverse colon (10.4%), 77.1% of the patients showed Borrmann I and II, 81.2% had cancers large than 5 cm in diameter. 95.8% of the cases metamorphosed from well differentiated adenocarcinoma. Squamous change in adenocarcinoma of the large intestine was found in advanced cases, thus it should be considered that this change occurs as a secondary metamorphosis of the adenocarcinoma. Lymph node metastasis was found in 54.2% of the patients.
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