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  • Title: [Comparison of the effectiveness of preoperative radiation and thermoradiation therapy in treating breast cancer].
    Author: Muravskaia GV, Pantiushenko TA, Fradkin SZ, Zhabrid EA, Moiseenko VV.
    Journal: Med Radiol (Mosk); 1984 Apr; 29(4):50-5. PubMed ID: 6717267.
    Abstract:
    Based on an analysis of the 3- and 5-year results of the combined treatment of 865 patients with breast cancer using 4 variants of radiation exposure in the preoperative period the following aspects are discussed: 1) the conventional variant of gamma-beam therapy at summary doses of 40-45 Gy is not an optimum variant of preoperative irradiation; 2) better results are achieved with the preoperative irradiation of the affected breast and zones of regional metastasis at a single dose of 4 Gy and a summary dose of 20 Gy; 3) a marked tendency towards achieving still better results of treatment and a statistically significant decrease in the frequency of distant metastases detected in the first 2 years after treatment are noted with the use of two other variants of preoperative exposure: an increase in the doses in tumor growth zones up to the level which is equivalent to a carcinocidal dose and a short course of preoperative irradiation (20 Gy) under the conditions of local UHF-hyperthermia.
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