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  • Title: Chiari malformation presenting as loss of cerebellar substance on computed tomography.
    Author: Gebarski SS, Greenberg HS.
    Journal: Surg Neurol; 1984 Jun; 21(6):562-4. PubMed ID: 6719328.
    Abstract:
    Cerebral computed tomography (CT) is the primary imaging modality in the investigation of suspected cerebellar degeneration. A case is presented in which an inaccurate clinical and radiologic diagnosis of olivo-pontocerebellar degeneration resulted from CT imaging demonstrating loss of cerebellar substance. Subsequent clinical recognition of downbeat nystagmus led to a diagnosis of Chiari malformation. This malformation was classified as a "severe" Chiari type I via clivomyelography and angiography. Surgical decompression resulted in marked clinical improvement. Visualization of the loss of cerebellar substance should not be considered to exclude Chiari malformation.
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