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  • Title: [Isoenzyme P of N-acetyl-beta-glucosaminidase in sera from patients with liver diseases (author's transl)].
    Author: Pott G, Eberhardt G, Gerlach U.
    Journal: Klin Wochenschr; 1978 Jul 01; 56(13):681-2. PubMed ID: 672139.
    Abstract:
    The isoenzyme P of N-Acetyl-beta-Glucosaminidase (beta-NAG) is demonstrated in sera from healthy persons and patients with acute and chronic liver diseases by electrofocusing in polyacrylamide gel. Elevation of isoenzyme P is observed only together with elevation of Glutamate-Pyruvate-Transaminase (GPT) in patients with acute and chronic liver diseases of different etiology and activity. The correlation between isoenzyme P and GPT is significant. On the contrary whole beta-NAG is elevated due the activity of the mesenchymal reaction in the injured liver tissue, not related to enzymes of the cytosol like GPT.
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