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  • Title: [Effect of glycerol on the capacity and conductivity of lipid bilayer membranes].
    Author: Rudenko SV, Gapochenko SD, Bondarenko VA.
    Journal: Biofizika; 1984; 29(2):223-6. PubMed ID: 6722192.
    Abstract:
    It is shown that glycerol addition to one side of BLM containing cholesterol leads to a significant decrease of its capacity, and the decrease rate is in indirect proportion to glycerol concentration. Washing out or addition of glycerol to another side results in a full or partial reconstitution of the capacity. The effect of glycerol on the BLM conductivity is manifested in its increase for membranes having specific conductivity above 2.10(-7) Om-1 X cm2. The peculiarity of glycerol is manifested in the fact that during definite period of time (20 +/- 30 min) the membrane is under "stress" condition with the characteristic current fluctuations, which may be compared with its medium meaning. Such condition is preserved up to the moment of BLM rupture. It is supposed that such effects are due to the big-scale reconstructions of membrane structure under the influence of glycerol.
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