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  • Title: Beyond the therapeutic window: a case presentation.
    Author: Schulz SC, Butterfield L, Garicano M, Narasimhachari N, Friedel RO.
    Journal: J Clin Psychiatry; 1984 May; 45(5):223-5. PubMed ID: 6725212.
    Abstract:
    The relationship of haloperidol dose and plasma concentration to psychotic symptoms of schizophrenia is described. The authors present evidence supporting a therapeutic window hypothesis, in which an individual patient's course follows an inverted U curve. The clinical implications for dosage strategies are discussed.
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