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  • Title: The effects of acetylcholine on bulbar respiratory related neurones. Consequences of anaesthesia by pentobarbital.
    Author: Morin-Surun MP, Champagnat J, Denavit-Saubie M, Moyanova S.
    Journal: Naunyn Schmiedebergs Arch Pharmacol; 1984 Mar; 325(3):205-8. PubMed ID: 6728036.
    Abstract:
    The effects of cholinergic agonists and antagonists applied by microiontophoresis to bulbar respiratory neurones were determined in different preparations: cats anaesthetized by pentobarbital and immobilized by gallamine triethiodide, intercollicular decerebrate cats either not immobilized or immobilized by gallamine triethiodide. Respiratory neurones located at the bulbar level exhibited a muscarinic cholinergic sensitivity in all preparations. Muscarinic responses were either excitatory or inhibitory. The number of neurones showing excitatory responses was lower under pentobarbital anaesthesia than in decerebrate cats.
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