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  • Title: [Arterial hypertension: adenocarcinoma of the kidney or bilateral renal artery stenosis$].
    Author: Beretta-Piccoli C, Tettamanti F, Crivelli PL, Weidmann P.
    Journal: Schweiz Med Wochenschr; 1984 Apr 28; 114(17):601-4. PubMed ID: 6729421.
    Abstract:
    In a 71-year-old female with severe hypertension, bilateral renal artery stenosis and renal adenocarcinoma, a renal vein renin study revealed suppressed renin secretion from the kidney with carcinoma and contralateral ischemia. The hypertension was not cured by surgical removal of the kidney with carcinoma. Hypertension is frequently noted in patients with renal adenocarcinoma (28% of 603 patients reported in the literature). This type of hypertension is frequently improved after removal of the tumor (83% of 36 surgically treated patients). In certain patients the pathogenesis of hypertension associated with renal adenocarcinoma may be related to renin secretion from the tumor or to renin activation due to regional ischemia caused by vascular compression. In other patients the renin-angiotensin system does not appear to play a pathogenic role in the development of hypertension associated with renal adenocarcinoma.
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