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  • Title: Age and the dexamethasone suppression test in depression.
    Author: Davis KL, Davis BM, Mathé AA, Mohs RC, Rothpearl AB, Levy MI, Gorman LK, Berger P.
    Journal: Am J Psychiatry; 1984 Jul; 141(7):872-4. PubMed ID: 6731636.
    Abstract:
    The authors examined the effects of age on plasma cortisol concentrations of 81 depressed men after dexamethasone administration. Dexamethasone nonsuppression was significantly more frequent in patients older than age 55 than those younger. Similarly, older patients had significantly higher postdexamethasone cortisol concentrations than younger patients at all time points sampled. These differences could not be attributed to severity or to the prevalence of psychosis in older and younger depressed patients.
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