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  • Title: [Automatization of heparin determination using chronometric evaluation of anti-Xa activity of the AT III-heparin complex].
    Author: Sampol J, Rossi JM, Lejay G.
    Journal: Ann Biol Clin (Paris); 1984; 42(1):21-3. PubMed ID: 6731952.
    Abstract:
    The authors describe an adaptation on a semi- automatique coagulometer KC 10 of a manual assay of anti-Xa activity of the Heparin-Antithrombin III Complex close to the technique described by Yin and al. ( Hepaclot - Stago ). The results show a good linearity and a good reproducibility, with a better sensitivity than the manuel method. Freezing has no influence. Significant differences were observed between our assay and the manuel anti-IIa assay. These last results neither depend on the administration route nor on the heparin batches.
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