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  • Title: [Acid-soluble, non-histone proteins in rat liver chromatin. Interaction with DNA].
    Author: Chikhirzhina GI, Bubiakina VV.
    Journal: Biokhimiia; 1984 Apr; 49(4):651-7. PubMed ID: 6733162.
    Abstract:
    Some properties of nonhistone proteins of rat liver chromatin (Mr 40 +/- 1 and 41 +/- 1 KD) are described. These proteins are abundant in monomeric particles formed at the early steps of chromatin fragmentation by Ca2+,Mg2+-DNase. The proteins are not extracted from chromatin by 5% HClO4 and 1 M NaCl, but can be extracted by 0.4 n H2SO4 and 2 M NaCl. Study on proteins binding to DNA demonstrated that in 0.05 M NaCl these proteins are bound both to bovine satellite DNA and to the plasmid pBR 322 DNA.
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