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  • Title: Microbial biodegradation of 4-chlorobiphenyl, a model compound of chlorinated biphenyls.
    Author: Massé R, Messier F, Péloquin L, Ayotte C, Sylvestre M.
    Journal: Appl Environ Microbiol; 1984 May; 47(5):947-51. PubMed ID: 6742836.
    Abstract:
    The biodegradation products of 4-chlorobiphenyl were analyzed in an Achromobacter sp. strain and a Bacillus brevis strain. Both strains generated the same metabolites, with 4-chlorobenzoic acid as the major metabolic product. Our results corroborate previous observations whereby most bacterial strains degrade the chlorobiphenyls via a major pathway which proceeds by an hydroxylation in position 2,3 and a meta-1,2 fission. However, we also detected several metabolites whose structure suggests the existence of other routes for the degradation of chlorinated biphenyls.
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