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  • Title: [Development of subtracted nephrogram using 131I-hippuran sequential scintigraphy (author's transl)].
    Author: Nishimura T, Kimura K.
    Journal: Radioisotopes; 1978 May; 27(5):255-9. PubMed ID: 674704.
    Abstract:
    Subtracted nephrogram was developed using 131I-hippuran sequential scintigraphy. An Anger-camera and on-line minicomputer system (HITAC-10, 16KW) was employed for data processing. In the present study, after 500microCi of 131I-hippuran was injected intravenously, sequential images were stored as 10-second frames of digitalized data for 20 minutes and these images were transferred into the magnetic tape. RI dynamic curves in the areas of interest such as substantial and pelvic regions were extracted by comparison with regional renograms with varimax method. Subtracted nephrogram was attempted which calculated the differences in RI concentration between two images of substantial and pelvic phase in the digitalized image and displayed as functional images on a CRT. These methods were applied clinically in various renal diseases. It was demonstrated that subtracted nephrogram was proved to be a method by which the dynamic process of renal function was represented by a single display. And subtracted nephrogram was shown to delineate the functioning renal substance and pelvis clearly and to correspond with the findings of pyelography. In conclusion, these method seemed to be useful for quantitative evaluation of substantial or pelvic function and for the differential diagnosis of various renal diseases.
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