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  • Title: Menstrual disorder after medical termination of pregnancy.
    Author: Mitra J, Mondal A, Khara BN, Chandra De R.
    Journal: J Indian Med Assoc; 1984 Jan; 82(1):4-6. PubMed ID: 6747323.
    Abstract:
    This study evaluated changes in menstrual cycle function and gynecologic abnormalities following medical termination of pregnancy. Of the 500 abortions, 90 by dilation and evacuation, 120 by intraamniotic hypertonic saline infusion, 210 by prostaglandin, and 180 by extraovular ethacridine lactate. Each case was followed for 1 year after the abortion procedure. All cases were 24-26 years of age. The menstrual cycle was considered to be irregular if the cycle was deferred by more than 7 days, with the irregularity persisting for more than 3 cycles. Changes in menstrual cycle function were considered significant if the duration of flow altered by more than or less than 1 day after abortion than that of the previous cycle. Both the dilatation and evacuation and intraamniotic hypertonic saline infusion procedures were associated with significant changes from regular to irregular cycles. This change occurred in 26.6% of women having the former procedure and 42.5% of those undergoing the latter procedure. Increased menstrual flow was noted in 26.6% of women undergoing dilatation and evacuation and in 26.5% of those receiving suction evacuation. Saline infusion abortion was followed by an absence of menstruation in 3 cases. The durationof the menstrual flow was significantly increased in 29.5% of women undergoing suction evacuation and in 23.4% of those receiving dilatation and evacuation. A high increase in the severity of dysmenorrhea was reported by 20% of cases receiving the menstrual regulation procedure and 50% of those undergoing saline infusion. However, a decrease in dysmenorrhea severity was noted for dilatation and evacuation (50%) and prostaglandin abortion (37.5%,. The incidence of gynecologic abnormalities noted at follow-up visits, most of which were related to infection, was highest among women who underwent both the dilatation and evacuation and saline infusion procedures.
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