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  • Title: [Serum prolactin levels following abortion in normal and molar pregnancy].
    Author: Shinkawa O, Furuhashi N, Hoshiai H, Fukaya T, Wada Y, Takahashi T, Tanaka M.
    Journal: Nihon Sanka Fujinka Gakkai Zasshi; 1984 Jun; 36(6):911-6. PubMed ID: 6747379.
    Abstract:
    The changes in serum specific hCG and prolactin levels were studied in 20 women after the evacuation of normal pregnancy at 5-10 weeks (group A) and 10 patients after the evacuation of molar pregnancy of 9-16 weeks (group B). The elimination of circulating hCG was faster in group A than in group B, and that in women after term delivery(group C)was faster than in both groups A and B. The half-life of the serum hCG level was 44.4 hrs in group A, 42.7hrs in group B, and 38.9hrs in group C, respectively. The mean level of serum prolactin in group A was 27.4ng/ml at 0 day, 64.5ng/ml at 4-7 days, and 31.9ng/ml at 13-15 days after evacuation, respectively. The surge was statistically significant. Though no regular tendency was found in the prolactin levels in group B, the levels were relatively higher than in group A and nonpregnant women. No correlation was found between hCG and prolactin levels in either group A or group B. The administration of drugs, such as methotrexate, did not affect the prolactin levels. On BBT, the resumption of ovulation tended to occur when the prolactin level, rather than the hCG level, returned to its normal range. The changes in serum specific human chorionic gonadotropin (hCG) and prolactin levels were studied in 20 women after the evacutaion of normal pregnancy at 5-10 weeks (group A) and 10 patients after evacuation of molar pregnancy of 9-16 weeks duration (group B). The elimination of circulating hCG was faster in group A than in group B; that in women after term delivery (group C) was faster than in either of the other groups. The 1/2-life of serum hCG levels was 44.4 hours in group A, 42.7 hours in group B, and 38.9 hours in group C. The mean level of serum prolactin in group A was 27.4 ng/ml at 0 days, 64.5 ng/ml at 4-7 days, and 31.9 ng/ml at 13-15 days after evacuation. The surge was statistically significant. Though no regular tendency was found in prolactin levels in group B, the levels were relatively higher than in group A and nonpregnant women. No correlation was found between hCG and prolactin levels in either A or B. The administration of drugs such as methotrexate did not affect prolactin levels. With regard to basal body temperature, the resumption of ovulation tended to occur when prolactin levels rather than hCG levels returned to the normal range. (author's modified)
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