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  • Title: Quantity and translation efficiency of liver microsomes in young and old rats following partial hepatectomy.
    Author: Mallonee RL, Garrison NE, Sellers CM.
    Journal: Comp Biochem Physiol B; 1982; 72(2):275-81. PubMed ID: 6749403.
    Abstract:
    1. Liver microsomal quantity decreased in young rats 2 days after partial hepatectomy or sham operation, increased to preoperative values by 8 days, and remained unchanged 16 days following surgery. 2. In old rats, microsomal quantity remained unchanged following surgery, but increased in sham-operated controls. 3. Translational efficiency of microsomes from young, sham-operated animals was unaffected, but decreased 2 days after partial hepatectomy. 4. In old, sham-operated controls, efficiency decreased, but remained unchanged 2 days after partial hepatectomy. 5. Eight and 16 days after surgery, efficiency of microsomes from young and old animals appeared indistinguishable, and were similar to those of adults before surgery.
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