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  • Title: [Pathological anatomy and pathogenesis of small intestine lesions due to opportunistic enterobacteria (Proteus and Klebsiella)].
    Author: Barshteĭn IuA, Anisimova IuN, Gandziĭ GP.
    Journal: Arkh Patol; 1982; 44(7):18-24. PubMed ID: 6751293.
    Abstract:
    Infection with opportunistic agents was reproduced in rabbits by introduction of Proteus and Klebsiella bacteria into a section of the narrowed (but not ligated) small intestine. The presence of infection was documented by clinical signs, isolation of the causative agents, and immunological changes. Light and electron microscopy revealed an inflammatory process of the type of catarrhal enteritis with predominant involvement of the epithelial sheet ("epithelitis") and reactive changes in the base of the mucous membrane and submucous layer. Morphological differences of the infections caused by Proteus and Klebsiella were demonstrated. The level and intensity of pathological changes appear to be associated with the degree of conditionality of the pathogenic properties of enterobacteria.
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