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  • Title: [Increased efficacy of allogenic bone marrow transplantation].
    Author: Fedotenkov AG, Danilova LA, Ignasheva LP.
    Journal: Biull Eksp Biol Med; 1982 Aug; 94(8):104-8. PubMed ID: 6751429.
    Abstract:
    Experiments made in vivo and vitro have demonstrated that conservation of allogeneic hemopoietic tissue with glycerin brings about a decrease in transplatation, homologous activity of T lymphocytes. Allogeneic bone marrow conserved with glycerin compares very favourably with freshly prepared allogeneic bone marrow since the transplant-versus-host reaction is attenuated under the effect of glycerin. Moreover, it shows a higher proliferative activity. The glycerin-induced reduction of the inactivating effect of lymphocytes against non-syngeneic colony-forming units enables the conserved bone marrow to be transplanted from several donors.
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