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  • Title: Platelet transfusion therapy in an alloimmunized patient. The value of crossmatch procedures for donor selection.
    Author: Hecht T, Wolf JL, Mraz L, Scott EP, Patz LD.
    Journal: JAMA; 1982 Nov 12; 248(18):2301-3. PubMed ID: 6752444.
    Abstract:
    A 51-year-old patient with acute myelogenous leukemia, who was alloimmunized to platelets, failed to show adequate platelet increments after receiving transfusions of HLA grade A-identical platelets. Only platelets from an HLA grade B-matching donor gave high increments. Several crossmatching procedures were used to select platelet donors. A correlation was seen between in vitro tests and in vivo response. HLA typing has limitations in the selection of platelet-compatible donors.
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