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  • Title: Pirenzepine in non-ulcer dyspepsia. A double-blind, placebo controlled trial.
    Author: Dal Monte PR, D'Imperio N, Accardo P, Daniotti S.
    Journal: Scand J Gastroenterol Suppl; 1982; 72():247-50. PubMed ID: 6753119.
    Abstract:
    Fifty patients (with non-ulcer dyspepsia) were admitted to a double-blind, placebo-controlled trial to study the effects of pirenzepine (100 mg/daily) on non-ulcer dyspepsia. Ten patients did not complete the trial. After 4 weeks of treatment, statistically significant improvement (P less than 0.001) was observed endoscopically in the pirenzepine group. The relief of dyspepsia was significantly greater in the pirenzepine-treated group. The tolerability of pirenzepine was good.
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