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  • Title: Videodensitometric processing of contrast two-dimensional echocardiographic data.
    Author: Meltzer RS, Roelandt J, Bastiaans OL, Piérard L, Serruys PW, Lancée CT.
    Journal: Ultrasound Med Biol; 1982; 8(5):509-14. PubMed ID: 6755850.
    Abstract:
    We developed a computer program to analyze videodensity changes due to contrast appearance within a given operator-designated rectangle using two-dimensional echocardiograms previously recorded on videotape. Videodensity curves have been obtained from two-dimensional echocardiographic recordings in 14 patients after a total of 32 injections of 5% dextrose solution into the left ventricle during cardiac catheterization. The resulting videodensity vs time curves have some characteristics of indicator-dilution curves. The decay phase of these curves is largely mono-exponential. Potential clinical applications of this technique in measurement of ejection fraction, cardiac output and shunt quantification are discussed, as well as some potential limitations.
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