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  • Title: Histopathology of the synovial membrane of peripheral joints in ankylosing spondylitis.
    Author: Revell PA, Mayston V.
    Journal: Ann Rheum Dis; 1982 Dec; 41(6):579-86. PubMed ID: 6756321.
    Abstract:
    The histological features of the synovial membrane of peripheral joints in ankylosing spondylitis are similar to those seen in rheumatoid arthritis. There is intimal cell hyperplasia, a diffuse lymphocyte and plasma cell infiltrate, and formation of lymphoid follicles. Peroxidase-antiperoxidase staining shows the presence of IgG-, IgA-, and IgM-containing plasma cells in ankylosing spondylitis. The percentage of IgM-containing cells is significantly lower in ankylosing spondylitis than in rheumatoid arthritis.
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